The PS2 version of Mana Khemia 2: Fall of Alchemy has a complete official English release (on PS2 and PSN for PS3). That’s the recommended way to experience the game in English without patch-related issues.
: The vast majority of the story dialogue, character quests, and specific alchemy recipes remain in Japanese. What Makes "Portable Plus" Different? mana khemia 2 portable plus english patch download