Wilms Tumor Ppt New |work| < BEST >

. While most cases are sporadic, about 10% are associated with specific genetic syndromes like Denys-Drash Beckwith-Wiedemann

| Therapy | Risk | |---------|------| | Doxorubicin | Cardiomyopathy (20% by 30 years) | | Abdominal radiation | Secondary cancers (osteosarcoma, breast), scoliosis | | Nephrectomy | Hypertension, proteinuria, CKD Stage 2–3 | | Vincristine | Neuropathy, constipation, hearing loss | wilms tumor ppt new

Wilms tumor (nephroblastoma) is the most common primary renal malignancy in children, typically presenting between ages 2 and 5. It arises from embryonic renal precursor cells and can be unilateral or, less commonly, bilateral. Early recognition, staging, and multidisciplinary treatment yield high cure rates in developed settings. Hematuria: Gross or microscopic blood in the urine

: Present in ~25% of patients due to increased renin activity . Diagnostic Workup Imaging:

Found in 25–60% of patients due to increased renin production. Hematuria: Gross or microscopic blood in the urine. General Symptoms: Fever, anorexia, or weight loss. 3. Diagnostic Workup Imaging: